Allergies:

"What are the Allergic Etiologies of Pruritus? Legitimacy of the Diagnostic Procedures for Allergy" 

When considering the correct etiological approach in the context of chronic pruritus, a distinction must be made between pruritus with and without skin lesions. While diagnostic procedures for allergy may be beneficial in the context of acute urticaria or contact eczema, their place is questionable with regard to other pruritic dermatoses. Find more details in the article of Dr Bruno Déchamps: “Allergy and Pruritus: What are the Allergic Etiologies of Pruritus? Legitimacy of the Diagnostic Procedures for Allergy” published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

Allergic rhinitis in children may lead to increased daytime fatigue as a result of impairment of sleep quality due to chronic inflammation of the nasal mucosa and consequent nasal congestion. Such fatigue could lead to under achievement in the scholastic environment.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at http://www.acii.net.

Allergy is the most prevalent chronic disease in Europe and it is on the rise. This informative brochure for patients is designed to explain different types and causes of allergy. In simple terms, it explains what allergy and allergic diseases are and the link between rhinitis and asthma. There is a self-evaluation questionnaire and allergy tests treatments and what the patient can do to help themselves are presented.

With GA²LEN Courtesy : www.ga2len.net

Allergy is the most prevalent chronic disease in Europe and it is on the rise. Rhinitis and asthma, two forms of allergic disease, may be inextricably linked with up to a third of rhinitis suffers going on to develop asthma within 10 years. Current research activities, patient education initiatives, diagnosis, and treatment are explored in this informative brochure which is geared towards primary care physicians.

With GA²LEN Courtesy : www.ga2len.net

Find more details regarding the role of antihistamines in treating allergic inflammation in the article of Prof Gianni Marone: "Does the Most Potent Antihistamine Also Have the Strongest Anti-inflammatory Effect?", published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

"Up to 80% of the medicines prescribed to infants or children [...] are used off-label”. 

There is a stringent need for pediatric studies. In the 21st century diagnostic and therapeutic decisions should be guided by the evidence based medicine. Consequently efficacy, safety and quality of every drug should be proven for any condition and every age group. However "Up to 80% of the medicines prescribed to infants or children are not licensed for this age group and are thus used off-label”. Find more details regarding drug research in pediatrics in the article of Prof Paul C. Potter: " Drug Research in Pediatrics: should it be stopped or promoted?", published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

"Is Receptor Occupancy relevant for the efficacy of an H1 Antihistamine?"

Find more details regarding the role of receptor occupancy in the article of Margherita Strolin Benedetti, Michel Gillard & Eugène Baltes: “Estimation of Receptor Occupancy: When Is This Relevant for the Efficacy of an H1 Antihistamine?” published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

Find more details regarding the impact of allergic rhinitis on the patients’ quality of life and also the importance of quality of life in relation with the pharmaco-economic parameters in the article of Prof Claus Bachert: "Is Patient Self-Management of Allergic Rhinitis Realistic?", published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

"Allergic Rhinitis is not a short-lived phenomenon, but rather a dynamic process characterized by an inflammatory response"

Immediate allergic symptoms such as runny nose, itchy nose and sneezing can no longer be considered as sufficient and reliable markers of an allergic reaction. Chronic "Minimal Persistent Inflammation" (MPI) exists besides classical symptoms and is detectable even in the absence of symptoms, during a quiescence phase of the allergic rhinitis. Therefore, any therapeutic strategy for the treatment of allergic rhinitis should focus on minimizing inflammatory phenomenon rather than only alleviating acute symptoms.
Find more details in the article "Minimal Persistent Inflammation in Allergic Rhinitis – Its Clinical Implications" by G. Walter Canonica & Ilaria Baiardini published in Allergy and Clinical Immunology International. 

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

"Modern life for an allergic patient: trick or treat?"

The modern allergic patient experiences show that the modern, mainly indoor lifestyle, as well as the numerous daily stressful situations badly influence his quality of life. World population is increasing everywhere on our planet. As important consequences, increased urbanization as well as associated air warming and air pollution could explain increased prevalence of allergic disease even more in urban area versus rural. Diesel particles can absorb allergens released by pollen grains and, as a consequence, prolong the presence of the allergen in the air, creating increased severity of the disease in urban areas. Thus urban patients are facing severe outdoor and indoor air and "social" pollution. Today's allergic rhinitis patients experience frequent, complex, severe and persistent symptoms, impairing their daily-life activities in our modern world.
Find more details regarding the patients' voice on their allergy in the article of Professor Erkka Valovirta: "The Ever Evolving Allergy - Real-Life Experiences of the Modern Allergic patient" published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.

Ragweed pollen is highly allergenic and can be transported over long distances. It causes severe symptoms including rhino-conjunctivitis and asthma. Its prevalence in Europe is steadily increasing. In certain regions, up to 80% of pollen-allergic patients exhibit positive results to skin prick or RAST assays. The severity of the problem may be exacerbated by environmental pollution and climate factors.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at http://www.acii.net.

An urban way of life appears to promote allergy. Among others, outdoor pollution, indoor air quality problems, and psychological stress are linked to urban areas. Patients face more allergens than before. Several new indoor and outdoor allergens have been identified and the patients are exposed to more allergens for a longer time each year. Thus there is a need for more comprehensive environmental programs against today's allergies.
Find more details on this interesting subject in the article of Ralph Mösges & Ludger Klimek " Today's allergies: Are there new factors that play a role?" published in Allergy and Clinical Immunology International.

IOA acknowledges ACII for the permission to publish this article. For more information on ACII please visit the journal's own website at www.acii.net.